Loic Mandine

AI-Generated picture based on me.

A young Machine Learning Engineer, currently doing a Master in Machine Learning at MILA Institute.

From my previous industrial jobs (2-year prof. experiences), I have strong experiences in Computer Vision & Deep Learning to the edge and their respective related subfields.

Real-time Deep Learning applications, that need to run fast on low-power devices, are my favorite playgrounds.

Nonetheless, from my academic background, I am also interested in Multimodal algorithms (CV + NLP) and Explainability and Adversarial ML.

Call for Collaboration

I am looking for an ML-related internship for this Summer 2024, in the scope of my academic degree (hence eligible for various fundings), starting from May 2024, minimum duration of 4 months

Currently based in Montreal, I am open to on-site or remote opportunities.

News

Aug 29, 2023	🧑‍🎓🧑‍🎓 Accepted at the MILA Institute for a D.E.S.S in Machine Learning 🧑‍🎓🧑‍🎓
Dec 2, 2022	💻 Thrilled to become a MARSSian as a Machine Learning Engineer 💻
Sep 11, 2022	🥳🥳 Officially graduated from Polytech Nice Sophia - Applied Mathematics and Modeling major, Data Science minor 🥳🥳
Apr 2, 2022	🥈 place in European AI Hackathon

Selected publications

Application of machine learning methods to guide patient management by predicting the risk of malignancy of Bethesda III-V thyroid nodules

Grégoire D’Andréa, Jocelyn Gal, Loïc Mandine, and 15 more authors

European Journal of Endocrinology, Feb 2023

Abs

Indeterminate thyroid nodules (ITN) are common and often lead to (sometimes unnecessary) diagnostic surgery. We aimed to evaluate the performance of two machine learning methods (ML), based on routinely available features to predict the risk of malignancy (RM) of ITN.Multi-centric diagnostic retrospective cohort study conducted between 2010 and 2020.Adult patients who underwent surgery for at least one Bethesda III-V thyroid nodule (TN) with fully available medical records were included. Of the 7917 records reviewed, eligibility criteria were met in 1288 patients with 1335 TN. Patients were divided into training (940 TN) and validation cohort (395 TN). The diagnostic performance of a multivariate logistic regression model (LR) and its nomogram, and a random forest model (RF) in predicting the nature and RM of a TN were evaluated. All available clinical, biological, ultrasound, and cytological data of the patients were collected and used to construct the two algorithms.There were 253 (19\%), 693 (52\%), and 389 (29\%) TN classified as Bethesda III, IV, and V, respectively, with an overall RM of 35\%. Both cohorts were well-balanced for baseline characteristics. Both models were validated on the validation cohort, with performances in terms of specificity, sensitivity, positive predictive value, negative predictive value, and area under the receiver operating characteristic curve of 90\%, 57.3\%, 73.4\%, 81.4\%, 84\% (CI95\%: 78.5\%-89.5\%) for the LR model, and 87.6\%, 54.7\%, 68.1\%, 80\%, 82.6\% (CI95\%: 77.4\%-87.9\%) for the RF model, respectively.Our ML models performed well in predicting the nature of Bethesda III-V TN. In addition, our freely available online nomogram helped to refine the RM, identifying low-risk TN that may benefit from surveillance in up to a third of ITN, and thus may reduce the number of unnecessary surgeries.